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DERMATOLIGIST APPROVED INGREDIENTS

3-o-Ethyl Ascorbic Acid 

A highly refined vitamin C derivative selected for exceptional stability, skin compatibility, and brightening performance. Clinically studied to support collagen synthesis, antioxidant defense, and visible tone correction, delivering radiance, dark spot reduction, and environmental defense at a skin-friendly pH with exceptional tolerance for sensitive skin.

A multi-layer hydration matrix combining acetyl-glucosamine, multi-weight hyaluronic acid, sodium PCA, polyglutamic acid, and pullulan to support the skin's moisture balance and visible clarity. Works through multiple water-binding and retention pathways to instantly reduce the appearance of dehydration lines and uneven texture.

Cultivated using award-winning aeroponic biotechnology, producing a phytonutrient-rich extract with over 2,000% rare phenylated flavonoid concentration compared to conventionally grown mulberry root. This patented botanical active helps protect skin architecture by supporting the integrity of collagen, elastin, and the extracellular matrix.

Aqua (Water), 3-O-Ethyl Ascorbic Acid, Propanediol, Glycerin, Heptyl Glucoside, C13-15 Alkane, Caprylyl Glycol, Leuconostoc/Radish Root Ferment Filtrate, Crithmum Maritimum Callus Culture Filtrate, Glycyrrhiza Glabra (Licorice) Root Extract, Morus Alba (Mulberry) Root Extract, Caffeyl Glucoside, Epigallocatechin Gallatyl Glucoside, Epigallocatechin Gallate, Acetyl Glucosamine, Madecassoside, Sodium Carboxymethyl Beta-Glucan, Proline, Hyaluronic Acid, Sodium Hyaluronate, Sodium Polyglutamate, Lecithin, Pullulan, Sodium PCA, Sodium Lactate, Dimethylmethoxy Chromanol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Heptyl Undecylenate, Xanthan Gum, Sodium Gluconate, Sclerotium Gum, Hamamelis Virginiana (Witch Hazel) Water, Citric Acid, Sodium Hydroxide, Silica, Alcohol.

Three Centers of Innovation One Formula

THE SUBSTANCE™ MASTER C SERUM

Born from a global network of specialized research environments, uniting Swiss antioxidant innovation with French plant-cell biotechnology and American clinical development. The result is a sophisticated pigmentation treatment engineered for stability, skin compatibility, and high performance.

Manufactured in an FDA-registered facility operating under cGMP and certified to ISO 22716, every stage of production is guided by precision, safety, and consistency.

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